Prostate ductal adenocarcinoma with prostate mucinous adenocarcinoma: a case report and literature review
10.3969/j.issn.1009-8291.2024.12.006
- VernacularTitle:前列腺导管腺癌合并黏液腺癌1例报告及文献复习
- Author:
Rexiati NIHATI
1
;
Hong CAO
2
;
Weizhe HAN
1
;
Zhizhuang CHEN
1
;
Jiageng SHI
1
;
Zhuang WU
3
;
Yuan LYU
4
;
Chunyong JIANG
5
;
Tao LIU
1
;
Yongzhi WANG
1
;
Xinghuan WANG
1
;
Zhonghua YANG
1
Author Information
1. Department of Urology, Zhongnan Hospital of Wuhan University, Wuhan 430072
2. Department of Pathology, Zhongnan Hospital of Wuhan University, Wuhan 430072
3. Department of Urology, China Resources WISCO General Hospital, Wuhan University of Science and Technology, Wuhan 430072
4. Department of Urology, Huangmei County People's Hospital, Huanggang 435500
5. Department of Urology, Danjiangkou First Hospital, Danjiangkou 442700, China
- Publication Type:Journal Article
- Keywords:
prostate cancer;
prostate ductal adenocarcinoma;
prostate mucinous adenocarcinoma;
prostate special antigen
- From:
Journal of Modern Urology
2024;29(12):1055-1059
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To summarize the clinical manifestations, pathological characteristics, treatment options and prognosis of the world's first case of prostate ductal adenocarcinoma (PDA) complicated with prostate mucinous adenocarcinoma (PMA). [Methods] The clinical and follow-up data of a patient with PDA and PMA treated in Zhongnan Hospital of Wuhan University were retrospectively analyzed, and relevant literature in PubMed and CNKI databases was retrieved. [Results] The patient sought medical attention due to dysuria, frequent urination, urinary urgency and urinary pain for more than half a year, and was admitted to hospital 3 times in total.The initial diagnosis upon the first admission was benign prostatic hyperplasia complicated with prostatic abscess.After 2 months, the patient was readmitted due to worsening symptoms, received transurethral bladder neck incision+ cystoscopy+ transurethral plasma resection of the prostate, and postoperative diagnosis confirmed PDA with local PMA.Three months after surgery, the patient had bleeding.After auxiliary examinations revealed extensive metastasis, he received hormonal therapy.After 9 months, the patient died due to multiple lung metastases. [Conclusion] Early diagnosis has a significant impact on the treatment and prognosis, but there have been no previous reports of PDA combined with PMA, so the lack of specific biomarkers in the early stage has led to missed diagnosis or misdiagnoses.There is no specific treatment for PDA with PMA. Radical prostatectomy was not satisfactory in the treatment of this case.
