Value of biotargeted drugs in airway mucus therapy of asthma
10.12092/j.issn.1009-2501.2024.04.009
- VernacularTitle:生物靶向药物在哮喘气道黏液栓治疗中的价值
- Author:
Duo MOU
1
;
Kexin LIU
;
Chun CHANG
Author Information
1. 北京大学第三医院呼吸与危重症医学科,北京 100080
- Keywords:
airway mucus;
asthma;
biotargeted drugs
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2024;29(4):423-426
- CountryChina
- Language:Chinese
-
Abstract:
Airway mucus plug is a common phe-notype in asthma that increases the risk of acute asthma attacks by causing aggravation of airflow obstruction.Given its important role in asthma,treatment targeting airway mucus plugs may be a strategy to control asthma progression and prevent fatal asthma exacerbations.Previous studies have shown that acidosophils and T2 type inflammation are related with the formation of mucus plugs,and bio-targeted drugs targeting the above pathways may be effective in the treatment of airway mucus plugs.
