A Case of Nocardiosis with CMV (Cytomegalovirus) Infection after Third Renal Transplantation in China.
- Author:
Seong Min KIM
1
;
Ji Hwan KIM
;
Mi Jung PARK
;
Chang Sue PARK
;
Jee Min JUN
;
Hyae Ju OH
;
Yong Kee PARK
;
Yong Hun SIN
;
Joong Kyung KIM
;
Jong In PARK
Author Information
1. Department of Internal Medicine, Bong seng Hospital, Busan, Korea. kidney119@yahoo.co.kr
- Publication Type:Case Report
- Keywords:
Nocardiosis;
Cytomegalovirus;
Third renal transplantation
- MeSH:
Bacterial Infections;
Bone Marrow;
China*;
Communicable Diseases;
Cytomegalovirus;
Cytomegalovirus Infections;
Encephalitis;
Endometritis;
Enteritis;
Female;
Ganciclovir;
Hepatitis;
Humans;
Immune System;
Kidney Transplantation*;
Korea;
Lymphoma;
Nocardia Infections*;
Opportunistic Infections;
Pneumonia;
Sarcoidosis;
Transplants
- From:The Journal of the Korean Society for Transplantation
2005;19(1):63-68
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
It has been well known that long-term immune suppression in renal transplant patients increases the possibility of complications. Infectious disease is one of the representative complications. We experienced a case of nocardiosis with cytomegalovirus infection after third renal transplantation in China. Nocardiosis is an important opportunistic infection in immunosuppressed patients, lymphoma, sarcoidosis, and organ transplant patients. CMV can cause severe hepatitis, pneumonitis, enteritis, endometritis, and encephalitis. It can depress bone marrow, and impair the immune system so as to increase other bacterial infection and trigger rejections. Third renal transplantation causes long-term immune suppression or over-immune suppression on transplant patients. Very few cases of third renal transplantation have been reported in Korea. We reduced the dose of immune- suppressants, and treated it successfully with ganciclovir and Trimethoprim/Sulfamethoxazole (Bactrim(R)).
