Disseminated Cytomegalovirus Infection after Renal Transplantation: A Case Report.
- Author:
Eun Ah HWANG
1
;
Seung Yeup HAN
;
Sung Bae PARK
;
Hyun Chul KIM
Author Information
1. Dongsan Kidney Institute, Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea. k780121@dsmc.or.kr
- Publication Type:Case Report
- Keywords:
Cytomegalovirus;
Ganciclovir-resistant;
Foscarnet;
Renal transplantation
- MeSH:
Adult;
Cytomegalovirus Infections*;
Cytomegalovirus*;
Foscarnet;
Ganciclovir;
Humans;
Kidney Transplantation*;
Mortality;
Transplantation;
Transplants
- From:The Journal of the Korean Society for Transplantation
2005;19(1):69-73
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cytomegalovirus (CMV) remains an important pathogen in organ transplant recipients, and ganciclovir has been the antiviral agent of choice both for prevention and treatment of CMV disease. Recently ganciclovir-resistant cytomegalovirus has been reported with increasing frequency in organ transplant recipient and is an emerging clinical problem in transplant recipients. Ganciclovir-resistant CMV infection has been associated with clinical progression of CMV disease and high mortality even with foscarnet therapy. We report here a case of disseminated ganciclovir-resistant CMV disease in a 34-year-old renal transplant recipient, who died of multiorgan failure despite treatment with both ganciclovir and foscarnet.
