Use of central neuromodulators in chronic cough
10.12092/j.issn.1009-2501.2024.04.011
- VernacularTitle:慢性咳嗽与中枢神经因子调节剂的利用
- Author:
Bingxian SHA
1
;
Haodong BAI
;
Wanzhen LI
;
Li YU
;
Xianghuai XU
Author Information
1. 同济大学附属同济医院呼吸与危重症医学科,上海 200065
- Keywords:
chronic cough;
neuromodulator;
cough hypersensitivity syndrome
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2024;29(4):432-439
- CountryChina
- Language:Chinese
-
Abstract:
Chronic cough is a common condition that imposes significant physical,psychological,and social burdens on patients.Although chronic cough is often associated with underlying condi-tions such as asthma,gastroesophageal reflux dis-ease,and eosinophilic bronchitis,some patients ex-perience uncontrollable coughing that is difficult to attribute to a specific cause.Many of these pa-tients exhibit clinical features of cough hypersensi-tivity syndrome,providing new directions for re-search into the treatment of chronic cough.As the pathophysiological mechanisms of chronic cough are further elucidated,treatment approaches for chronic cough are entering a new stage of develop-ment.This article summarizes and discusses the mechanisms and clinical evidence of central neuro-modulators used in the treatment of chronic cough,suggesting promising clinical applications for these drugs in the future.
