Diagnosis and treatment of 281 elderly patients with pulmonary ground-glass opacity: A retrospective study in a single center
- VernacularTitle:老年肺结节患者281例外科诊疗的单中心回顾性研究
- Author:
Lei SU
1
;
Yi ZHANG
1
;
Yan GAO
2
;
Bing WEI
3
;
Tengteng WANG
1
;
Yuanbo LI
1
;
Kun QIAN
1
;
Peilong ZHANG
1
;
Leiming WANG
4
;
Xiuqin WEI
5
Author Information
1. Department of Thoracic Surgery, Xuanwu Hospital, Capital Medical University, Beijing, 100053, P. R. China
2. Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, 100053, P. R. China
3. Department of Pulmonary and Critical Care Medicine, Xuanwu Hospital, Capital Medical University, Beijing, 100053, P. R. China
4. Department of Pathology, Xuanwu Hospital, Capital Medical University, Beijing, 100053, P. R. China
5. Endoscopic Center, Plastic Surgery Hospital, Chinese Academy of Medical Sciences, Beijing, 100144, P. R. China
- Publication Type:Journal Article
- Keywords:
Elderly patients;
ground-glass opacity;
imaging features;
postoperative pathology
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2025;32(01):94-99
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the diagnosis and treatment strategies for elderly patients with ground-glass opacity (GGO). Methods The imaging features and postoperative pathological findings of the elderly patients with pulmonary GGO receiving surgery in our hospital from 2017 to 2019 were retrospectively analyzed. The patients were divided into an elderly patient group and a non-elderly patient group based on their age. Results Finally 575 patients were included in the study. There were 281 elderly patients, including 83 males and 198 females, with an average age of (67.0±5.3) years. There were 294 non-elderly patients, including 88 males and 206 females, with an average age of (49.1±7.3) years. Compared with the non-elderly patients, elderly GGO patients showed the following distinct clinical features: long observation time for lesions (P=0.001), high proportion of rough edges of GGO (P<0.001), significant pleural signs (P＜0.001) and bronchial signs (P＜0.001), and high proportion of type Ⅱ-Ⅳ GGO (P<0.001), lobectomy type (P=0.013), and invasive lesions reported in postoperative pathology (P<0.001). There was no statistical difference in the average hospital stay between the two groups (P=0.106). Multivariate logistic regression analysis showed that GGO diameter and GGO type were the main factors affecting the operation. Observation time, GGO diameter, GGO type and pleural signs were the main influencing factors for postoperative pathological infiltrative lesions. The cut-off value of GGO diameter in predicting infiltrating lesions was 10.5 mm in the elderly patients group. Conclusion The size and type of GGO are important factors in predicting invasive lesions and selecting surgical methods. Elderly patients with radiographic manifestations of type Ⅱ-Ⅳ GGO lesions with a diameter greater than 10.5 mm should be closely followed up.
