Calculation of retention and excretion fractions for uranium intake via wounds based on ICRP Report 137
10.13491/j.issn.1004-714X.2024.06.003
- VernacularTitle:基于ICRP137号出版物的伤口摄入铀的滞留与排泄分数计算
- Author:
Jieying LEI
1
;
Yang ZHANG
1
;
Bin ZHANG
1
;
Ming XU
1
;
Wei SHENG
1
;
Gaofeng SUN
1
Author Information
1. Northwest Institute of Nuclear Technology, Xi'an 710024 China.
- Publication Type:OriginalArticles
- Keywords:
Intake via wound;
Uranium;
Retention fraction;
Excretion fraction
- From:
Chinese Journal of Radiological Health
2024;33(6):631-637
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the retention and excretion fractions for uranium intake via wounds in the organs of adult reference computational phantom, and to improve the evaluation of health risks associated with radioactive isotopes intake via wounds. Methods A software for evaluation of the internal radiation dose was developed by combining the wound model in International Commission on Radiological Protection Report 156 and the systemic models in the International Commission on Radiological Protection Report 130 and the subsequent Occupational Intakes of Radionuclides series reports. This study was conducted to calculate the uranium retention fractions in adult reference individuals following ingestion through wounds of seven categories of uranium: weakly retained, moderately retained, strongly retained, very strongly retained, colloids, particles, and fragments. We assessed the retention fractions in the wound sites, bones, and liver, as well as the excretion fractions in urine and feces, and compared these results with authoritative results. Results The retention and excretion fractions of 238U and 235U in different forms of intake via wounds showed consistent variations. The retention fractions of weak and moderate uranium in wounds could be ignored after 1 000 d. The retention fractions of strong, avid, and colloid uranium were 10−4 to 10−5 after 10 000 d. A significant portion of the uranium present in the forms of particles and fragments exhibited long-term retention in wounds. The bone retention fractions were 1 to 2 orders of magnitude higher than the liver retention fractions. Following the intake of soluble and insoluble uranium, the retention fractions in these two organs decreased and increased, respectively, compared with those observed on the first day. The urinary excretion fractions were approximately 2 orders of magnitude higher than the fecal excretion fractions. Following the intake of soluble and particulate uranium, the excretion fractions decreased. At 1 000 d after the intake of uranium in the form of fragments, the urinary and fecal excretion fractions were 10−6 and 10−8, respectively. Conclusion The calculation results validated the accuracy of the established models, providing data support for the assessment of internal exposure doses in individuals following uranium wound contamination incidents.
