Textual Research of Key Information of Classic Formula Xieqingwan Based on Ancient and Modern Literature
10.13422/j.cnki.syfjx.20241411
- VernacularTitle:经典名方泻青丸的关键信息古今文献考证
- Author:
Yujie CHANG
1
;
Lyuyuan LIANG
1
;
Jialei CAO
1
;
Xinghang LYU
1
;
Wenxi WEI
2
;
Xiaofang WANG
3
;
Huizhen ZHANG
4
;
Sai REN
5
;
Mengqi WANG
1
;
Bingqi WEI
2
;
Bingxiang MA
1
Author Information
1. Hospital of Pediatrics of The First Affiliated Hospital of Henan University of Chinese Medicine， Zhengzhou 450099，China
2. Traditional Chinese Medicine College of Henan University of Chinese Medicine， Zhengzhou 450046，China
3. Hebei University of Chinese Medicine， Shijiazhuang 050000， China
4. College of Orthopedics， Henan University of Chinese Medicine， Zhengzhou 450046，China
5. First Clinical Medical College， Henan University of Chinese Medicine， Zhengzhou 450046，China
- Publication Type:Journal Article
- Keywords:
Xieqingwan;
historic origin;
formula meaning;
effect;
clinical application
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2025;31(4):226-234
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveThis paper aims to systematically collect and organize ancient and modern clauses and studies containing Xieqingwan， excavate and analyze the key information of Xieqingwan， and provide a reference for facilitating the development of the classic formula Xieqingwan. MethodsThe composition， dosage， decocting methods， usage， and other key information of Xieqingwan in ancient traditional Chinese medicine books were collected and analyzed by means of literature research and metrological methods. The modern clinical application of Xieqingwan was summarized. ResultsA total of 42 pieces of effective data involving 32 ancient traditional Chinese medicine books were collected. Xieqingwan was first recorded in Xiaoer Yaozheng Zhijue. The drug origin of this formula is basically clear in the ancient traditional Chinese medicine books. The modern drug usage and decocting method were as follows： Angelicae Sinensis Radix， Gentianae Radix et Rhizoma， Chuanxiong Rhizoma， Gardenia seeds， Radix et Rhizoma Rhei， Notopterygii Rhizoma et Radix， and Saposhnikoviae Radix were grounded to fine powder， decocted with honey， and finally formed into pills with the size of a chicken head （1.5 g）. It was suggested that half a pill or one pill were taken for one dose with warm Lophatheri decoction and sugar. The indications and clinical application had developed from the recordings in Xiaoer Yaozheng Zhijue and evolved from pediatrics to ophthalmic otolaryngology， neurology， dermatology， digestion， and respiratory diseases. The main pathogenesis of these diseases is heat in the liver meridian and is treated. The effect of Xieqingwan is "clearing away heat and toxicity， removing fire and relaxing the bowels， and dispersing swelling and relieving pain". It is recommended to use the corresponding preparation methods in the 2020 Edition of Pharmacopoeia of the People's Republic of China. Modern clinical studies are centered around the clinical application of Xieqingwan， which is often modified and used in treating Tourette syndrome， herpes， febrile convulsion， sleepwalking， and insomnia. ConclusionThis paper conducts a thorough textual research of the key information of Xieqingwan， induces its historic evolution， and confirms its key information， so as to provide a reference for the future development of Xieqingwan.
