Collection, storage and utilization of lung transplant tissue samples

Yixing LI; Xue Shi; Hongyi Wang; Runyi Tao; Ye Sun; Ailing SU; Liyan Tong; Jinteng Feng; Yanpeng Zhang; Shuo LI; Yawen Wang; Guangjian Zhang

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Collection, storage and utilization of lung transplant tissue samples

VernacularTitle:肺移植组织样本的采集、储存与利用
Author: Yixing LI ¹ ; Xue SHI ² ; Hongyi WANG ¹ ; Runyi TAO ¹ ; Ye SUN ² ; Ailing SU ² ; Liyan TONG ¹ ; Jinteng FENG ¹ ; Yanpeng ZHANG ¹ ; Shuo LI ¹ ; Yawen WANG ² ; Guangjian ZHANG ¹
Author Information

1. Department of Thoracic Surgery, the First Affiliated Hospital of Xi'an Jiaotong University, Key Laboratory of Enhanced Recovery After Surgery of Intergrated Chinese and Western Medicine, Xi'an 710000, China.
2. .
Publication Type:ReviewArticle
Keywords: Lung transplantation; Lung tissue; Human genetic resource; Specimen collection; Storage; Ethics; Biobank; Technical specification
From: Organ Transplantation 2025;16(1):147-155
CountryChina
Language:Chinese
Abstract: After continuous development and improvement, lung transplantation has become the preferred means to treat a variety of benign end-stage lung diseases. However, the field of lung transplantation still faces many challenges, including shortage of donor resources, preservation and maintenance of donor lungs, and postoperative complications. Lung tissue samples removed after lung transplantation are excellent clinical resources for the study of benign end-stage lung disease and perioperative complications of lung transplantation. However, at present, the collection, storage and utilization of tissue samples after lung transplantation are limited to a single study, and unified technical specifications have not been formed. Based on the construction plan of the biobank for lung transplantation in the First Affiliated Hospital of Xi'an Jiaotong University, this study reviewed the practical experience in the collection, storage and utilization of lung transplant tissue samples in the aspects of ethical review, staffing, collection process, storage method, quality control and efficient utilization, in order to provide references for lung transplant related research.