Discussion on the Experience of ZHANG Zhiyuan in Using Large Doses of Fuzi （Aconiti Lateralis Radix Praeparata） Based on the Quantity-Effect Relationship
10.13288/j.11-2166/r.2025.02.003
- VernacularTitle:从量效关系探讨张志远运用大剂量附子经验
- Author:
Zhanhui DUAN
1
;
Guirong LIU
2
;
Jinping YANG
1
Author Information
1. Institute for Literature and Culture of Chinese Medicine，Shandong University of Traditional Chinese Medicine，Jinan，250355
2. School of Traditional Chinese Medicine，Shandong University of Traditional Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Fuzi （Aconiti Lateralis Radix Praeparata）;
doses;
experience of famous doctor;
ZHANG Zhiyuan
- From:
Journal of Traditional Chinese Medicine
2025;66(2):119-122
- CountryChina
- Language:Chinese
-
Abstract:
To summarize Prof. ZHANG Zhiyuan's clinical experience in using large doses of Fuzi （Aconiti Lateralis Radix Praeparata）. The effect of Fuzi is based on its acrid and hot propoerties， warming and invigorating yang qi and running without guard. The application of large doses of Fuzi can be categorized into raw and processed， with common dosage ranging from 30 g to 60 g of raw Fuzi， and 15 g to 30 g， 30 g to 60 g of processed Fuzi. The quantity-effect relationship of the large dose of Fuzi is summarized as 15 g to 30 g of processed Fuzi could warm water， warm yang and eliminate timidity， as the treatment of asthma with deficiency cold phlegm， edema of yang deficiency， and panic and timidity of yang deficiency； 30 g to 60 g of processed Fuzi could tonify fire， warm the meridians and collaterals， assist yang to dispel cold and relieve pain， as the treatment of coldness in the limbs， abdominal pain， pain in the joints of the limbs， and loose stools due to deficient yang qi and exuberant internal yin cold； 30 g to 60 g raw Fuzi could restore yang to save from collapse， as the treatment of yang depletion after profuse sweating and vomiting. At the same time， different dosages of Fuzi were flexibly paired with other medicines， i.e.， 15 g to 30 g of processed Fuzi was paired with Mahuang （Ephedrae Herba） and Xixin （Asari Radix et Rhizoma） to assist yang to dispel coldness， 30 g to 60 g of processed Fuzi was paired with Baizhu （Atractylodis macrocephalae rhizoma） or Wuzhuyu （Euodiae Fructus） to warm yang and dispel dampness， and 30 g to 60 g of raw Fuzi was paired with Shanzhuyu （Corni Fructus） to tonify both yin and yang.
