Research progress of Application of polysaccharide hydrogel based on dynamic covalent bond in drug delivery and tissue repair
DOI:10.13748/j.cnki.issn1007-7693.20223433
- VernacularTitle:基于动态共价键的多糖水凝胶在药物递送及组织修复中的应用研究进展
- Author:
YE Fan
1
;
LI Siyu
1
;
ZHANG Yun
2
,
3
;
DANG Yunjie
1
;
DU Qing
1
Author Information
1. Department of Pharmaceutics, School of Pharmacy, Hebei Medical University, Shijiazhuang 050017, China
2. Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences &
3. Peking Union Medical College, Beijing 100193, China
- Publication Type:Journal Article
- Keywords:
hydrogel / polysaccharide / dynamic bond / drug delivery
- From:
Chinese Journal of Modern Applied Pharmacy
2023;40(21):3047-3052
- CountryChina
- Language:Chinese
-
Abstract:
Abstract: Hydrogels are widely used in biomedical fields such as drug delivery, wound dressings and tissue engineering because of their good biocompatibility and biodegradability. According to the source of material, it can be divided into synthetic material hydrogel and natural material hydrogel. Natural polysaccharide hydrogel not only can be used as material, but also has unique pharmacological activity and better mechanical properties, gradually become the preferred material. Dynamic covalent hydrogels have attracted much attention due to their structural flexibility, self healing performance and environmental responsiveness. In this paper, the dynamic bond mode natural polysaccharide hydrogel systems are classified and summarized, and the research status of the construction of this kind of hydrogel in drug delivery and tissue repair are summarized, to provide reference for the application of new polysaccharide hydrogels in clinical application.
