Discussion on the pathogenesis and treatment of non-alcoholic fatty liver disease in postmenopausal women based on the theory of "deficient qi and stagnation"
10.3969/j.issn.1006-2157.2024.12.014
- VernacularTitle:基于“虚气留滞”理论探讨女性绝经后非酒精性脂肪性肝病的病机及治疗
- Author:
Mingyao XU
1
;
Wenyuan SU
1
;
Jing WU
2
;
Jiawen HE
3
;
Haowei ZHANG
1
;
Jinjuan LI
2
;
Jia YUE
2
;
Yan ZHANG
1
Author Information
1. Basic College of Gansu University of Chinese Medicine
2. School of Public Health of Gansu University of Chinese Medicine
3. Affiliated Hospital of Nanjing University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
non-alcoholic fatty liver disease;
deficient qi and stagnation;
women;
postmenopausal;
nourishing deficiency and resolving stagnation
- From:
Journal of Beijing University of Traditional Chinese Medicine
2024;47(12):1745-1752
- CountryChina
- Language:Chinese
-
Abstract:
Non-alcoholic fatty liver disease is a common chronic liver disease in clinical practice. In recent years, with increasing social attention to the health of women and the elderly, the prevention and treatment of non-alcoholic fatty liver disease after menopause has increasingly become a research hotspot in metabolic diseases. This study explores the pathogenesis and treatment method of non-alcoholic fatty liver disease in postmenopausal women based on the theory of "deficient qi and stagnation" and combined with the physiological and pathological characteristics of postmenopausal women and the Western medicine understanding of non-alcoholic fatty liver disease. We believe that the pathogenesis of non-alcoholic fatty liver disease in postmenopausal women is rooted in the "deficient qi" caused by depletion of liver and kidney essence and blood. The imbalance between the physical and functional aspects of the liver due to this "deficient qi" is the primary factor, while the "stagnation" of phlegm and blood stasis is the manifestation. Furthermore, the "deficient qi" and "stagnation" reinforce each other, with the deficiency leading to stagnation and stagnation exacerbating the deficiency, thus accelerating the progression of the disease. The treatment approach should be one that combines nourishing deficiency and resolving stagnation, addressing both root cause and maifestations. Given the female characteristic of "the liver as the innate organ" and the post-menopausal physiological state of "gradual decline of kidney essence", it is important to focus on nourishing the liver and kidneys, nurturing the liver′s physical body while maintaining its function, and also promoting the circulation of qi, resolving phlegm, and invigorating blood circulation to remove blood stasis. This approach aims to reduce the accumulation of lipids in the liver, offering a new perspective and approach for the treatment of non-alcoholic fatty liver disease in post-menopausal women with traditional Chinese medicine.
- Full text:202501071539259349Discussion on the pathogenesis and treatment of non-alcoholic fatty liver disease in postmenopausal women based on the theory of “deficient qi and stagnation”.pdf