The First Case of Novel Influenza A (H1N1) Fatality in Korea.
10.4046/trd.2010.68.6.350
- Author:
Hee Yun SEOL
1
;
Jung Seop EOM
;
Mi Hyun KIM
;
Woo Hyun CHO
;
Ji Eun KIM
;
Ki Uk KIM
;
Doo Soo JEON
;
Hye Kyung PARK
;
Yun Seong KIM
;
Min Ki LEE
;
Soon Kew PARK
Author Information
1. Department of Internal Medicine, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea. uk303@hanmail.net
- Publication Type:Case Report
- Keywords:
Influenza A Virus, H1N1 Subtype;
Pneumonia, Viral;
Respiratory Insufficiency;
Death
- MeSH:
Anoxia;
Anti-Bacterial Agents;
Dyspnea;
Emergencies;
Fever;
Heart Arrest;
Humans;
Influenza A Virus, H1N1 Subtype;
Influenza, Human;
Korea;
Lung;
Middle Aged;
Orthomyxoviridae;
Oseltamivir;
Pneumonia, Viral;
Polymerase Chain Reaction;
Respiration, Artificial;
Respiratory Distress Syndrome, Adult;
Respiratory Insufficiency;
Shock, Septic;
Thorax
- From:Tuberculosis and Respiratory Diseases
2010;68(6):350-353
- CountryRepublic of Korea
- Language:English
-
Abstract:
Here we report the first fatality caused by H1N1 influenza virus infection with acute respiratory distress syndrome in Korea. A 55-year-old man presented at our emergency department with dyspnea, fever, diffuse myalgia and malaise. Bilateral lung air-space consolidation was detected on his initial chest radiograph combined with severe hypoxemia. He was supported by mechanical ventilation and treated with antibiotics. A nasopharyngeal aspirate was positive for influenza A rapid antigen and oseltamivir was started on day 3 of admission. The nasal swab sample was positive for influenza H1N1 virus by real-time reverse-transcriptase polymerase chain reaction. Despite aggressive treatment, he had refractory hypoxemia and uncontrolled septic shock. On day 5 of admission he went into cardiac arrest and expired.
