Dilution and slow injection reduces the incidence of rocuronium-induced withdrawal movements in children.
10.4097/kjae.2011.61.6.465
- Author:
Young Hee SHIN
1
;
Chung Su KIM
;
Jong Hwan LEE
;
Woo Seog SIM
;
Justin Sangwook KO
;
Hyun Sung CHO
;
Hui Yeon JEONG
;
Hye Won LEE
;
Sang Hyun KIM
Author Information
1. Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. jonghwanlee75@gmail.com
- Publication Type:Original Article
- Keywords:
Child;
Injections;
Intravenous;
Movement;
Pain;
Rocuronium
- MeSH:
Androstanols;
Child;
Humans;
Incidence;
Research Personnel;
Unconsciousness
- From:Korean Journal of Anesthesiology
2011;61(6):465-469
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: The aim of this study was to evaluate whether slow injection of diluted rocuronium could reduce rocuronium-induced withdrawal movements effectively in children. METHODS: After loss of consciousness, rocuronium 0.6 mg/kg was administered into 171 children according to the pre-assigned groups as follows: Group CF, injection of non-diluted rocuronium over 5 seconds; Group CS, injection of non-diluted rocuronium over 1 minute; Group DF, injection of diluted rocuronium (10 times) over 5 seconds; Group DS, injection of diluted rocuronium over 1 minute. An investigator who was blind to the injection techniques recorded patient movements followed by rocuronium injection. RESULTS: The incidence of withdrawal movement in Group CF was highest among the groups (all P < 0.0001). Moreover, withdrawal movement was less frequently observed in Group DS than in Groups CS and DF (P = 0.021 and P = 0.007, respectively). CONCLUSIONS: Slow injection of diluted rocuronium reduced the incidence of withdrawal movements in children.
