Effect of transcranial direct current stimulation based on music therapy on insomnia:a randomized controlled trial
10.3969/j.issn.1006-9771.2024.10.010
- VernacularTitle:音乐治疗基础上联合经颅直流电刺激对失眠效果的随机对照试验
- Author:
Siyan CAI
1
;
Yingjie FAN
;
Huifang TIAN
;
Chunya XIA
;
Juan ZHANG
;
Min SU
Author Information
1. 苏州大学附属第四医院(苏州市独墅湖医院)康复医学科/苏州大学康复研究所,江苏 苏州市 215124
- Keywords:
insomnia;
transcranial direct current stimulation;
music therapy;
depression;
anxiety;
lectroencephalography;
transcranial Doppler;
randomized controlled trial
- From:
Chinese Journal of Rehabilitation Theory and Practice
2024;30(10):1193-1202
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of transcranial direct current stimulation(tDCS)based on music therapy on insomnia. Methods From July,2023 to April,2024,70 patients with insomnia in the Fourth Affiliated Hospital of Soochow Univer-sity were randomly divided into control group(n=35)and observation group(n=35).Both groups accepted mu-sic therapy;moreover,the observation group accepted tDCS,and the control group accepted sham tDCS,for four weeks.They were assessed with Pittsburgh Sleep Quality Index(PSQI)total score and sub-score,Hamilton De-pression Scale 17-item(HAMD-17),Hamilton Anxiety Scale(HAMA),Chinese version of Stress Perception Scale(CPSS);and the relative power of resting-state electroencephalography(EEG)and mean blood flow veloci-ty(Vm)of each cerebral artery with transcranial Doppler were measured before and after treatment. Results Five cases dropped down in the control group,and four in the observation group.PSQI total score and sub-score,HAMD-17 score,HAMA score and CPSS score(|t|>3.503,P<0.01)in the observation group decreased after treatment,and were less in the observation group than in the control group(|t|>2.304,P<0.05),except sleep duration,sleep efficiency and CPSS scores.The relative power of δ and θ increased in the observation group,and decreased in α,β and γ(|t|>6.468,P<0.001),and were better in the observation group than in the control group(|t|>2.395,P<0.05).The Vm of each artery increased in the observation group(|t|>4.624,P<0.001),and were more in the observation group than in the control group(|t|>2.147,P<0.05). Conclusion tDCS based on music therapy may further improve sleep quality and EEG activity,increase cerebral blood flow velocity,and reduce adverse emotions in insomnia patients.
