Anesthetic experiences of myxoma removal surgery in two patients with Carney complex: A report of two cases.
10.4097/kjae.2011.61.6.528
- Author:
Young Mi KANG
1
;
Yoon Hee KIM
Author Information
1. Department of Anesthesiology and Pain Medicine, College of Medicine, Chungnam National University, Daejeon, Korea. yhkim0404@cnu.ac.kr
- Publication Type:Case Report
- Keywords:
Anesthesia;
Carney complex;
Myxoma
- MeSH:
Anesthesia;
Carney Complex;
Cyclic AMP-Dependent Protein Kinases;
Endocrine Gland Neoplasms;
Hemorrhage;
Humans;
Myxoma;
Neurilemmoma;
Skin
- From:Korean Journal of Anesthesiology
2011;61(6):528-532
- CountryRepublic of Korea
- Language:English
-
Abstract:
Carney complex is an autosomal dominant disorder that occurs due to a mutation in PRKAR1A, which encodes protein kinase A. The clinical features are multiple endocrine gland neoplasms, skin tumors, pigmented skin lesions, myxomas, and schwannomas. In Carney complex, the cardiac myxoma is a common co-morbidity. It occurs in multiples, during young age, regardless of gender and cardiac chamber and is known to recur frequently. Therefore there are high risks of adhesion and massive bleeding due to repeated surgeries. Such surgical risks account for over 50% of disease-specific mortality of Carney complex patients. Here, we present anesthetic experiences of myxoma removal surgery in two patients with Carney complex.
