Exploration and application of the evaluation criterion for the clinical rational use of Dahuang Zhechong Capsule
10.3969/j.issn.1006-2157.2024.10.015
- VernacularTitle:大黄?虫胶囊临床合理用药评价标准的探索及应用
- Author:
Jin LIU
1
;
Xujie ZANG
;
Peng XU
;
Jian QI
;
Tianyu ZHANG
;
Tao FU
;
Wei YUAN
;
Pengcheng YUAN
;
Haile FENG
Author Information
1. 中国中医科学院西苑医院药学部 北京 100091
- Keywords:
Dahuang Zhechong Capsule;
rational use of drug;
evaluation criterion;
outpatient prescription;
indication
- From:
Journal of Beijing University of Traditional Chinese Medicine
2024;47(10):1449-1456
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the evaluation basis of the clinical rational use of Dahuang Zhechong Capsule and to establish its rationality evaluation criterion to promote the sensible use of Dahuang Zhechong Capsule.Methods The rationality evaluation criterion for Dahuang Zhechong Capsule was formulated by referring to the package insert,treatment guidelines,and other literature.According to the criterion,270 outpatient prescriptions using Dahuang Zhechong Capsule in Xiyuan Hospital,China Academy of Chinese Medical Sciences were reviewed from January to June 2020.The indication,usage and dosage,drug combination,and repeated administration were analyzed.The pharmaceutical intervention was performed to address the problems found in the prescription reviews,and 328 outpatient prescriptions using Dahuang Zhechong Capsule in October 2020 were reevaluated.Results The irrational use rate of Dahuang Zhechong Capsule from January to June 2020 was 42.22％(114 cases),including 108(40％)cases of inappropriate indications,five(1.85％)cases of improper usage and dosage,and one(0.37％)case of inappropriate administration route.However,the pharmaceutical intervention in October 2020 remarkably reduced the irrational use rate of Dahuang Zhechong Capsule(4.27％,14 cases),all of which were inappropriate indications.Conclusion Dahuang Zhechong Capsule is being used irrationally;therefore,establishing an evaluation criterion is required.The specific situation of irrational drug use can be identified by prescription review according to its rationality evaluation criterion to manage its clinical use better and promote its rational use.
