Research progress on circulating tumor cells for early diagnosis and prognosis of pancreatic cancer

Author: Mengruo Jiang ¹ ; Lisi Peng ¹ ; Chuanchao Xia ^{1
,

2} ; Shiyu Li ¹
Author Information

1. Dept of Gastroenterology , Changhai Hospital Afiliated to Naval Medical University , Shanghai 200433
2. Dept of Gastroenterology , The First Hospital Afiliated to Zhejiang University School of Medicine , Hangzhou 310003
Publication Type:Journal Article
Keywords: circulating tumor cells; pancreatic cancer; liquid-based biopsy; biomarkers
From: Acta Universitatis Medicinalis Anhui 2024;59(11):2059-2064
CountryChina
Language:Chinese
Abstract: Abstract:Pancreatic cancer is a highly malignant gastrointestinal cancer with a poor prognosis, and early diagnosis remains challenging. The use of reliable biomarkers can significantly enhance the early evaluation and management of this disease. Circulating tumor cells(CTCs) are released into the bloodstream and can be obtained easily through minimally invasive liquid-based biopsy, making them promising candidates for early tumor diagnosis, prognosis assessment, and monitoring therapeutic responses. This paper reviews the advancements in CTCs detection technology and their clinical applications in pancreatic cancer over the past decade, both domestically and internationally, which offer a new perspective on the early diagnosis and prognosis of pancreatic cancer.
Full text:2024122614304862275循环肿瘤细胞在胰腺癌早期诊断及预后中的研究进展_蒋梦若.pdf