Discussion on the mechanism of the"inflammation-cancer transformation"in primary multiple pulmonary nodules
10.3969/j.issn.1006-2157.2024.10.004
- VernacularTitle:原发性多发肺结节"炎癌转化"机制探讨
- Author:
Mengqian LI
1
;
Xiaomei ZHANG
;
Liangduo JIANG
;
Yuxin LAI
Author Information
1. 北京中医药大学东方医院 北京 100078
- Keywords:
primary multiple pulmonary nodules;
inflammation-cancer transformation;
health qi deficiency;
emotional depression;
dampness phlegm and blood stasis accumulation;
preventive treatment of disease
- From:
Journal of Beijing University of Traditional Chinese Medicine
2024;47(10):1355-1359
- CountryChina
- Language:Chinese
-
Abstract:
Primary multiple pulmonary nodules have a high incidence,and the size and number of pulmonary nodules on computed tomography images increase with time.Postoperative pathology of multiple pulmonary nodules shows chronic inflammation,adenomatoid change,carcinoma in situ,microinvasive carcinoma,infiltrating carcinoma,and other forms.There is a possibility of"inflammation-cancer transformation"in multiple pulmonary nodules with prolonged time and external irritation.The accumulation of dampness phlegm and blood stasis is the basis of the theory of"inflammation-cancer transformation."Healthy qi deficiency is the key to the"inflammation-cancer transformation."Qi and yang deficiency are the root cause of healthy qi depletion.Emotional depression,dampness,phlegm,and blood stasis transforming into toxins provide the impetus for"inflammation-cancer transformation."There are struggle between healthy qi and evil qi,and waxing and waning of dampness,phlegm and blood stasis in the process of"inflammation-cancer transformation."The dampness phlegm and blood stasis will increase when evil qi increases and healthy qi decreases.In contrast,the size,number,and malignancy of nodules will increase during healthy qi deficiency,showing a dynamic shift from inflammation to atypical adenomatous hyperplasia to cancer.The dampness phlegm and blood stasis will be absorbed as the healthy qi increases and evil qi decreases so that lung cancer can be reversed.External irritation,such as acute inflammatory stimulation,may accelerate the transformation of"inflammation-cancer"in multiple pulmonary nodules.
