Clinical research on corneal epithelium remodeling after small incision lenticule extraction and femtosecond laser-assisted in situ keratomileusis
10.3980/j.issn.1672-5123.2025.1.07
- VernacularTitle:SMILE与FS-LASIK术后角膜上皮重塑的临床研究
- Author:
Yangjing ZHANG
1
,
2
;
Liwei MA
1
,
2
;
Fan ZHANG
1
,
2
;
Chunmei KE
1
,
2
;
Ruifu WANG
1
,
2
;
Lipye ZU
1
,
2
Author Information
1. Aier Eye Medical Center of Anhui Medical University, Hefei 230031, Anhui Province, China
2. Urumqi Aier Eye Hospital, Urumqi 830000, Xinjiang Uyghur Autonomous Region, China
- Publication Type:Journal Article
- Keywords:
small incision lenticule extraction(SMILE);
femtosecond laser-assisted in situ keratomileusis(FS-LASIK);
corneal epithelium remodeling;
optical coherence tomography(OCT)
- From:
International Eye Science
2025;25(1):37-41
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To compare the changes in corneal epithelial thickness(CET)after small incision lenticule extraction(SMILE)and femtosecond laser-assisted in situ keratomileusis(FS-LASIK).METHODS: A total of 187 patients(187 eyes)who underwent either SMILE or FS-LASIK at Urumqi Aier Eye Hospital between December 2022 and November 2023 were collected. The patients were divided into SMILE group and FS-LASIK group according to surgical methods. The CET of the patients was measured by optical coherence tomography(OCT)system before surgery and at 1 wk, 1, 3, and 6 mo postoperatively.RESULTS: Changes in corneal epithelial thickness(△CET)in the central, paracentral, and mid-peripheral regions were compared at 6 mo postoperatively. The SMILE group was characterized by the most significant thickening in the central area and the least thickening in the mid-peripheral area; while the FS-LASIK group was characterized by the most significant thickening in the paracentral area and the least thickening in the mid-peripheral region. At 1 wk, 1, 3, and 6 mo postoperatively, within the 0-7 mm corneal area, the △CET for both the SMILE and FS-LASIK groups was correlated with the preoperative spherical equivalent.CONCLUSION: Within 6 mo postoperatively, both SMILE and FS-LASIK showed a similar trend in epithelial thickening but with distinct characteristics. The change in corneal epithelial thickness for both procedures was positively correlated with the preoperative diopter.
