Establishment and Application of Drug Use Evaluation Standard of Ticagrelor
10.13748/j.cnki.issn1007-7693.20232185
- VernacularTitle:替格瑞洛药物利用评价标准的构建和应用
- Author:
Yu ZHANG
1
,
2
;
Mi ZHENG
1
,
2
;
Jing ZHANG
3
,
4
;
Maogui ZENG
1
,
2
;
Jinhua ZHANG
5
Author Information
1. Department of Pharmacy, the Second People&rsquo
2. s Hospital Affiliated to Fujian University of Traditional Chinese Medicine, Fuzhou 350003, China
3. Department of Pharmacy, the Affiliated People&rsquo
4. s Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou 350004, China
5. Department of Pharmacy, Fujian Maternity and Child Health Hospital, Fuzhou 350001, China
- Publication Type:Journal Article
- Keywords:
ticagrelor ； drug use evaluation； expert consultation
- From:
Chinese Journal of Modern Applied Pharmacy
2024;41(10):1394-1402
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE :To establish the drug use evaluation(DUE) standard of ticagrelor, and to provide a reference for the rational clinical application of ticagrelor.
METHODS
Based on the ticagrelor drug label, related guidelines and literature, combined with clinical expert consultation results, DUE standard from three levels (indications, medications and medication results) was established. A retrospective survey was conducted to evaluate the inpatients using ticagrelor from January 2021 to December 2021 in the Second Affiliated Hospital of Fujian University of Traditional Chinese Medicine.
RESULTS
The DUE of ticagrelor was divided into three levels, including 3 first-level indexes, 14 second-level indexes and 60 third-level indexes. A total of 263 cases of using ticagrelor were included, of which the irrational rate was 72.62%. The irrational cases were mainly off-label use (60.08%), inappropriate drug conversion(14.83%) and unreasonable usage and dosage(5.70%), etc.
CONCLUSION
The established DUE standard of ticagrelor is scientific, practical and feasible, which can provide reference for clinical rational drug use and prescription evaluation.
