Analysis of Clinical Application on Prescriptions of Toxic Traditional Chinese Medicine Decoction Pieces in Oncology Outpatient Department
10.13748/j.cnki.issn1007-7693.20230412
- VernacularTitle:肿瘤科毒性中药处方临床应用分析
- Author:
Shanshan QIAN
1
;
Xiaoming GAO
1
;
Mingchen HAN
1
;
Manqin YANG
1
Author Information
1. The Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine, Hefei 230061, China
- Publication Type:Journal Article
- Keywords:
toxic traditional Chinese medicine；oncology outpatient department；overdose
- From:
Chinese Journal of Modern Applied Pharmacy
2024;41(8):1099-1105
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE :To analyze the use and distribution characteristics of toxic traditional Chinese medicine decoction pieces in oncology outpatient department, and to provide data reference for the safe and rational use of toxic traditional Chinese medicine decoction pieces in clinical applications.
METHODS
The 838 prescriptions data of toxic traditional Chinese medicine from the Oncology Outpatient Department of The Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine in 2022 were collected and made retrospective statistical analysis of patient gender, age, clinical diagnosis, variety of toxic traditional Chinese medicine, frequency of use, frequency of overdose, and combination use of toxic traditional Chinese medicine.
RESULTS
Among the 838 prescriptions of toxic Chinese herbal medicines, 22 toxic Chinese herbal medicines were involved, accounting for 81.48% of the hospital's toxic Chinese herbal medicines. The majority of prescriptions (217 cases, accounting for 25.89%) aged 50 to 60 years old. Most of the single prescriptions were concentrated in 11 to 15, and the toxic Chinese herbal decoction pieces were mainly used in various tumor diseases, digestive system diseases and gynecological diseases, etc. In addition to golden larch bank, ginkgo and centipede, the other toxic traditional Chinese medicines all had the overdose problem. 231 prescriptions of toxic traditional Chinese medicine were used in combination with≥2 , with 190 prescriptions of 2 ingredients being the most commonly used (accounting for 22.67%). There were 78 incompatibilities, most of which were the combination of Aconiti Lateralis Radix Praeparata and Pinelliae Rhizoma. It was used to treat chronic Atrophic gastritis, insomnia and depression.
CONCLUSION
Toxic traditional Chinese medicine decoction pieces are widely used in oncology department. However, the overdose phenomenon is serious, it is necessary to be aware of the potential risks of overdose and combination of toxic traditional Chinese medicine. Therefore, it is necessary to further strengthen drug management, promote rational application, and ensure patient medication safety.
