An analysis of risk factors for infectious endophthalmitis requiring evisceration or enucleation
10.19405/j.cnki.issn1000-1492.2022.02.026
- Author:
Feng Wang
1
;
Huan He
2
;
Jinxia Zhai
2
Author Information
1. Dept of Ophthalmology, The First Afiliated Hospital of Anhui Medical University, Hefei 230022
2. Dept of Occupational and Environmental Health ,School of Public Health ,Anhui Medical University, Hefei 23002
- Publication Type:Journal Article
- From:
Acta Universitatis Medicinalis Anhui
2022;57(2):301-305
- CountryChina
- Language:Chinese
-
Abstract:
Objective :To analyze the risk factors for endophthalmitis requiring evisceration or enucleation.
Methods :The charts of 121 eyes of 121 inpatients with endophthalmitis were retrospectively reviewed , and the group that required evisceration or enucleation (24 patients) with those that received salvaging therapies (97 patients) were compared. Age , sex , medication history , past medical history , clinical manifestation , Leukocyte counts and treatment progression were retrospectively analyzed.
Results :Twenty four eyes( 19. 8% )underwent enucleation or evisceration. The proportion of corneal ulcerative endophthalmitis ( 33. 3% ) and endogenous endophthalmitis (25. 0% ) in evisceration or enucleation group was greater than that in the salvaging group ( 1. 0% , 4. 1% ) (P < 0. 001) . The group of eviscerated or enucleated eyes was older (P < 0. 05] , had poorer initial visual acuity [(2. 9 ± 0. 2) LogMAR vs (2. 3 ± 0. 5) LogMAR , P < 0. 001] , had longer duration before intervention ( 15. 8 d vs 4. 6
d , P < 0. 05) , and had more Leukocyte counts [( 12. 8 ± 5. 6) × 109/L vs (9. 1 ± 3. 3) × 109/L , P < 0. 005 ] . With Logistic regression analysis , corneal ulcer, endogenous endophthalmitis , initial vision , leukocyte counts , duration before intervention were the risk factor for evisceration or enucleation ( OR = 343. 283 , OR = 22. 608 , OR = 1 920. 384 , OR = 1. 341 , OR = 1. 167 ) .
Conclusion :The most common cause of evisceration or enucleation caused by infectious endophthalmitis are infections from corneal ulcer and from endogenous source. The risk factors for endophthalmitis requiring evisceration or enucleation would be considered to be corneal ulcer endophthalmitis , endogenous endophthalmitis , initial vision , leukocyte counts , and duration before intervention.
- Full text:202412191445244725感染性眼内炎转归至眼球摘除...眼内容剜除术的危险因素分析_汪枫.pdf
