Relationship Between the Duration of Perioperative Antibiotic Use and Postoperative Infection in HIV/AIDS Patients Undergoing Cesarean Section
10.13748/j.cnki.issn1007-7693.20222447
- VernacularTitle:HIV/AIDS患者剖宫产术围手术期抗菌药物使用疗程与术后感染的关系
- Author:
Jing ZHOU
1
;
Yuan ZHANG
2
,
3
;
Songlong LI
1
;
Qi WANG
1
;
Jianhua YU
4
;
Fugen WANG
1
Author Information
1. Hangzhou Xixi Hospital Department of Pharmacy
2. The Xiaoshan Third People&rsquo
3. s Hospital, Hangzhou 311251, China
4. Hangzhou Xixi Hospital Department II of Infectious Diseases, Hangzhou 310023, China
- Publication Type:Journal Article
- Keywords:
cesarean section ；antibiotics； course of treatment； infection
- From:
Chinese Journal of Modern Applied Pharmacy
2024;41(7):979-982
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE :To investigate the relationship between the course of antibiotics during perioperative period and postoperative infection in pregnant women with human immunodeficiency virus/acquired immune deficiency syndrome(HIV/AIDS) undergoing cesarean section, and to guide the rational use of antibiotics in clinical practice.
METHODS
A total of 53 cesarean section women in the hospital from January 2014 to September 2022 were chosen as research objects. According to the course of antibiotics, the puerperae were divided into two groups. The treatment course of antibiotics in the study group(n=31) was >24 h and ≤48 h, and the control group(n=22) was ≤24 h. The postoperative wound healing, inflammatory indexes, postoperative infection rate, and postoperative hospital stay were observed.
RESULTS
There was no significant difference in postoperative body temperature, white blood cell count, neutrophil ratio, C-reactive protein, postoperative hospital stay, wound healing grade and postoperative infection rate between the study group and the control group.
CONCLUSION
Antibiotics for HIV/AIDS patients during perioperative period of cesarean section for <24 h may play a better role in preventing postoperative infection.
