Quality Standard of Tibetan Medicine "Yajima" (Chrysosplenium Axillare)
10.13748/j.cnki.issn1007-7693.20223244
- VernacularTitle:藏药亚吉玛(长梗金腰)药材质量标准研究
- Author:
Gang REN
1
;
Chaowei PU
1
;
Jingjing WEN
2
;
Wei JIANG
1
;
Guoyue ZHONG
1
;
Weizao LUO
3
;
Zhen NI
4
;
Jiamei XIANG
1
Author Information
1. Jiangxi University of Chinese Medicine Research Center of Natural Resources of Chinese Medicinal Materials and Ethnic Medicine
2. Jiangxi University of Chinese Medicine College of Science and Technology, Nanchang 330004, China
3. Chongqing Institute of Traditional Chinese Medicine, Chongqing 400060, China
4. Institute for Food and Drug Control of Xizang Autonomous Region, Lhasa 850000, China
- Publication Type:Journal Article
- Keywords:
Chrysosplenium axillare ；quality standard ； TLC ； characteristic chromatogram ； HPLC
- From:
Chinese Journal of Modern Applied Pharmacy
2024;41(4):469-475
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE :To establish the quality standards of medicinal materials in light of related methods in the general principles of part four of Chinese Pharmacopoeia(2020 Edition), and to conduct systematic research on the Tibetan medicine "Yajima"(Chrysosplenium axillare).
METHODS
The powder characteristics of medicinal materials were described by microscopic identification method. Silica gel GF254 thin-layer plate was employed to establish a TLC identification method with 5-O-demethylapulein and oxyayanin A as reference substances. Loss on drying, total ash, acid-insoluble ash and ethanol-soluble extractives of 10 batches of Chrysosplenium axillare were determined according to the general principles of part four of Chinese Pharmacopoeia(2020 Edition). HPLC was used to establish the characteristic chromatogram of Chrysosplenium axillare, and the content determination method was established with chrysosplenoside I(CI) and chrysosplenoside A(CA) as the quality control index components of Chrysosplenium axillare.
RESULTS
The water content, total ash, acid-insoluble ash, ethanol-soluble extractive and the content of CI and CA of all samples varied in the ranges of 9.17%−12.52%, 14.11%−16.74%, 1.50%−4.72%, 32.77%−40.30%, 0.30%−0.99% and 0.28%−0.88%, respectively.
CONCLUSION
The identification and content determination methods of Yajima(Chrysosplenium axillare) are established for the first time. The methods are easy to operate and exclusive, which is of great significance to accurately evaluate the internal quality of medicinal materials and ensure the quality of drug used.
