Outcome of Cadaveric Kidney Transplantation from Expanded Criteria Donors.
- Author:
Ja Yong PARK
1
;
Jang Hee CHO
;
Young Deuk YOON
;
Eun Joo SONG
;
Mi Kyung JIN
;
Chung Hoon YU
;
Hee Yeon JUNG
;
Jeong Hoon LIM
;
Yong Bong SHIN
;
Ji Young CHOI
;
Se Hee YOON
;
Sun Hee PARK
;
Chan Duck KIM
;
Yong Lim KIM
Author Information
1. Department of Internal Medicine, Kyungpook National University School of Medicine and Clinical Research Center for ESRD, Daegu, Korea. ylkim@knu.ac.kr
- Publication Type:Original Article
- Keywords:
Kidney transplantation;
Cadaver;
Graft survival
- MeSH:
Brain Death;
Cadaver;
Glomerular Filtration Rate;
Graft Survival;
Humans;
Hypertension;
Kidney;
Kidney Transplantation;
Retrospective Studies;
Tissue Donors;
Transplantation, Homologous;
Transplants
- From:Korean Journal of Medicine
2011;80(4):408-418
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND/AIMS: The Korean Network for Organ Sharing (KONOS) was established in 2000, and the KONOS criteria for expanded-criteria donors (ECD) have since been applied to kidney allocation from deceased donors. The outcome of cadaveric kidney transplantation from ECD according to KONOS criteria has not been investigated. METHODS: Seventy-seven cadaveric kidney transplants from January 2003 to December 2009 were recruited retrospectively. Factors that influence the glomerular filtration rate (GFR) of graft kidneys up to 36 months after transplantation were evaluated. Postoperative renal function and allograft and patient survival in the ECD group (n = 28) were compared with those in the standard-criteria donor (SCD) group (n = 49). RESULTS: The GFR of graft kidneys was different according to donor GFR, age, hypertension history, and cause of brain death. In the ECD group, GFR was lower than that in the SCD group by KONOS criteria. No differences in allograft or patient survival were observed until 3 years after kidney transplantation. CONCLUSIONS: Cadaveric kidney transplantation using the ECD by KONOS criteria is acceptable in term of graft and 3-year patient survival, although the GFR was lower in the ECD than in the SCD group.
