A Case of Multiple Solitary Plasmacytoma Recurring in Multiple Visceral Organs.
- Author:
Ik Chan SONG
1
;
Seung Woo BAEK
;
Kyu Seop LEE
;
Gak Won YUN
;
Young Jun YANG
;
Jin Man KIM
;
Deog Yeon JO
Author Information
1. Department of Internal Medicine, Chungnam National University College of Medicine, Daejeon, Korea. deogyeon@cnu.ac.kr
- Publication Type:Case Report
- Keywords:
Multiple solitary plasmacytoma;
Viscera
- MeSH:
Aged;
Biopsy;
Bone Marrow;
Boronic Acids;
Buttocks;
Dexamethasone;
Humans;
Male;
Pancreas;
Plasmacytoma;
Pyrazines;
Rare Diseases;
Recurrence;
Ribs;
Spine;
Stomach;
Viscera;
Bortezomib
- From:Korean Journal of Medicine
2011;80(5):609-614
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Multiple solitary plasmacytoma is a very rare disease entity, which occurs in up to 5% of patients with solitary plasmacytomas. We report an atypical case of multiple solitary plasmacytoma that recurred in multiple visceral organs without any evidence of bone marrow involvement. A 68-year-old male presented with voiding difficulty. Twenty months earlier, he had been placed on local radiotherapy for solitary plasmacytomas in the right 6th rib and right iliac bone. Recurrences were noted 14 and 12 months later in several ribs and the 5th cervical vertebra, respectively. These were well controlled with local radiotherapy and conventional systemic chemotherapy. He had multiple soft tissue masses in the stomach, pancreas, pelvic cavity, and right buttock. An endoscopic biopsy of the gastric mass confirmed the diagnosis of plasmacytoma. Local radiotherapy to the pelvic mass and systemic therapy consisting of bortezomib and dexamethasone were given, and he has been well for 8 months.
