Reappraisal of ABO-Blood Group Testing for Neonates: Can We Omit Back Typing?
10.17945/kjbt.2024.35.2.135
- Author:
Han Joo KIM
1
;
Kiwook JUNG
;
Yousun CHUNG
;
Hyungsuk KIM
;
Dae-Hyun KO
Author Information
1. Department of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
- Publication Type:Opinion
- From:Korean Journal of Blood Transfusion
2024;35(2):135-136
- CountryRepublic of Korea
- Language:English
-
Abstract:
ABO-blood typing typically involves both front typing (cell typing) and back typing (serum typing) to ensure accurate determination of blood type. However, in neonates, back typing is frequently omitted due to their immature immune system. If an institution chooses red blood cells (RBCs) that match the neonate's blood type, omitting back typing could lead to unexplained cross-matching incompatibilities. Therefore, blood banks should be cautious with neonatal blood typing and transfusion practices to ensure transfusion safety.