Study on evaluation of bioavailability of nifedipine tablets
- Author:
Pham Hue Minh
- Publication Type:Journal Article
- Keywords:
nifedipine
- MeSH:
Nifedipine;
Biological Availability;
tablets
- From:Pharmaceutical Journal
1999;282(10):19-21
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
The HPLC method described herein has sufficient sensitivity to determine the pharmacokinetic parameters of nifedipine in plasma. A single dose cross study was carried out in volunteers comparing the test sustained release nifedipine formulation to Adalat retard tablets. Pharmacokenetic variables were calculated from the nifedipine plasma concentration data and evaluated statistically. The results showed the test formulation to be bioequivalent to the reference tablets.
