Four Cases of Acquired Aplastic Anemia Affecting an Entire Family after Ingesting Ganoderma lucidum.
- Author:
Joo Hyuk JUNG
1
;
Hyun Woo LEE
;
Yoo Jin LEE
;
Hye Ran LEE
;
Tae Hyun UM
;
Ji Yeon PARK
;
Seong Yoon YI
Author Information
- Publication Type:Case Report
- Keywords: Aplastic anemia; Medicinal plants; Ganoderma lucidum
- MeSH: Adult; Anemia, Aplastic*; Anti-Bacterial Agents; Biopsy; Colony-Stimulating Factors; Fever; Ganoderma; Granulocytes; Humans; Pancytopenia; Plants, Medicinal; Reishi*; Wine
- From:Korean Journal of Medicine 2015;88(1):94-100
- CountryRepublic of Korea
- Language:Korean
- Abstract: We report four cases of Ganoderma lucidum-induced aplastic anemia involving members of the same family. A 33-year-old man and three family members were admitted to the hospital due to fever and pancytopenia. The illness arose after ingesting herbal wine containing G. lucidum 2 weeks earlier. A bone-marrow biopsy showed hypocellularity in three of the four family members (the exception was the one who died). They were treated with supportive management, including transfusions, granulocyte colony stimulating factor, and empirical antibiotics for neutropenic fever. The pancytopenia improved 4-5 weeks after the symptoms first appeared.