Cancer therapy‑related cardiac dysfunction and the role of cardiovascular imaging: systemic review and opinion paper from the Working Group on Cardio‑Oncology of the Korean Society of Cardiology
10.1186/s44348-024-00014-5
- Author:
Iksung CHO
1
;
Seng‑Chan YOU
;
Min‑Jae CHA
;
Hui‑Jeong HWANG
;
Eun Jeong CHO
;
Hee Jun KIM
;
Seong‑Mi PARK
;
Sung‑Eun KIM
;
Yun‑Gyoo LEE
;
Jong‑Chan YOUN
;
Chan Seok PARK
;
Chi Young SHIM
;
Woo‑Baek CHUNG
;
Il Suk SOHN
Author Information
1. Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea
- Publication Type:REVIEW
- From:
Journal of Cardiovascular Imaging
2024;32(1):13-
- CountryRepublic of Korea
- Language:English
-
Abstract:
Cardio-oncology is a critical field due to the escalating significance of cardiovascular toxicity as a side effect of anti‑ cancer treatments. Cancer therapy-related cardiac dysfunction (CTRCD) is a prevalent condition associated with car‑ diovascular toxicity, necessitating effective strategies for prediction, monitoring, management, and tracking. This comprehensive review examines the definition and risk stratification of CTRCD, explores monitoring approaches during anticancer therapy, and highlights specific cardiovascular toxicities linked to various cancer treatments. These include anthracyclines, HER2-targeted agents, vascular endothelial growth factor inhibitors, immune checkpoint inhibitors, chimeric antigen receptor T-cell therapies, and tumor-infiltrating lymphocytes therapies. Incorporating the Korean data, this review offers insights into the regional nuances in managing CTRCD. Using systematic follow-up incorporating cardiovascular imaging and biomarkers, a better understanding and management of CTRCD can be achieved, optimizing the cardiovascular health of both cancer patients and survivors.
