Effects of blood pressure variability on the progression and prognosis of carotid artery stenosis in elderly patients with cerebral infarction
10.3969/j.issn.1006-2483.2024.06.035
- VernacularTitle:血压变异致老年脑梗死患者颈动脉狭窄进展及预后的影响
- Author:
Pengcheng WAN
1
,
2
;
Bin XUE
2
,
3
Author Information
1. Department of Neurology , Chengdu Qingbaijiang District People'
2. s Hospital , Chengdu , Sichuan 610300 , China
3. Department of Cardiology , Chengdu Qingbaijiang District People'
- Publication Type:Journal Article
- Keywords:
Cerebral infarction;
Blood pressure variability;
Degree of carotid artery stenosis;
Vascular events;
Correlation
- From:
Journal of Public Health and Preventive Medicine
2024;35(6):152-156
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the effect of blood pressure variability (BPV) on the progression and prognosis of carotid artery stenosis in elderly patients with cerebral infarction. Methods A total of 98 elderly patients with cerebral infarction admitted from May 2019 to May 2022 were selected as the observation group, and 100 healthy people with physical examination during the same period were enrolled as the control group. According to the degree of carotid artery stenosis, the elderly patients with cerebral infarction were divided into four groups. The blood pressure variability parameters in each group were compared, and the relationship between BPV and the degree of carotid artery stenosis was analyzed. The risk factors of vascular events were analyzed and the predictive efficiency of BPV on vascular events was evaluated. Results The BPV parameter values in the observation group were higher than those in the control group (P<0.05), while the nocturnal decline rate of blood pressure was lower than that in the control group (P<0.05). The higher the degree of carotid artery stenosis, the higher the BPV parameter value and the lower the nocturnal decline rate of blood pressure (P<0.05). The proportion of total non-dipper type in the severe stenosis group was higher than that in the moderate stenosis group, mild stenosis group and non-stenosis group (P<0.05). Spearman correlation analysis showed that the BPV parameter values were positively correlated with the degree of carotid artery stenosis, and the nocturnal decline rate of blood pressure was negatively correlated with the degree of carotid artery stenosis (all P<0.05). Multivariate logistic regression analysis showed that the increases of BPV parameter values were all risk factors for vascular events in elderly patients with cerebral infarction (P<0.05). Receiver operating characteristic (ROC) curve analysis revealed that among the BPV parameters, dSSD had the highest efficiency in predicting the occurrence of vascular events in elderly patients with cerebral infarction. Conclusion BPV significantly affects the progression and prognosis of carotid artery stenosis in elderly patients with cerebral infarction.
