Research progress on clock genes and Parkinson's disease
10.3969/j.issn.1006-2483.2024.06.027
- VernacularTitle:时钟基因与帕金森病研究进展
- Author:
Yilin ZHANG
1
;
Junrou ZHANG
2
;
Piye NIU
2
Author Information
1. School of Basic Medicine, Capital Medical University , Beijing 100059 , China
2. Key Laboratory of Environmental Toxicology , School of Public Health , Capital Medical University , Beijing 100059 , China
- Publication Type:Journal Article
- Keywords:
Human papillomavirus;
Genotype distribution;
Prevalence;
Distribution characteristics
- From:
Journal of Public Health and Preventive Medicine
2024;35(6):117-122
- CountryChina
- Language:Chinese
-
Abstract:
The circadian rhythm is commonly present in mammals, and its maintenance is regulated by clock genes. In recent years, an increasing number of studies have shown that the polymorphism and expression of clock genes are abnormal in patients with Parkinson's disease. This article reviews the research progress of clock genes, CLOCK, BMAL1, PER, REV-ERBα, and CRY, as well as the pathogenesis of Parkinson's disease, which is helpful to further explore the role of clock genes and circadian rhythm disorders in the pathogenesis of Parkinson's disease. It provides ideas for further research on the mechanism of Parkinson's disease.
