Viral test in clusters of diarrhea in Xicheng Distract of Beijing in 2017-2022
10.3969/j.issn.1006-2483.2024.06.016
- VernacularTitle:2017—2022年北京市西城区聚集性腹泻疫情分析
- Author:
Haiyang CUI
1
;
Yanli JI
1
;
Bo JIN
1
;
Jun XU
1
;
Zhe LEI
1
;
Fang MIAO
1
Author Information
1. Xicheng Center for Disease Control and Prevention , Beijing 100120 , China
- Publication Type:Journal Article
- Keywords:
Clusters of diarrhea;
Morbidity;
Positive rate;
Norovirus;
Genetype
- From:
Journal of Public Health and Preventive Medicine
2024;35(6):72-76
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the epidemiological patterns and pathogens of clusters of diarrhea in Xicheng Distract , Beijing during 2017-2022 , in order to update the policy of prevention. Mehods Between January 2017 and December 2022, stool samples of patients and partly cooks in clusters of diarrhea were collected and tested by Real-time PCR for Rotavirus, Norovirus, Adenovirus, Sapovirus and Astrovirus. Part of ORF1/ORF2 from Norovirus positive samples were amplified using RT-PCR. PCR products were sequenced and the genetypes were determined. Results Four hundreds and one clusters of diarrheas were reported. Among them , 369 were reported in kindergartens, primary schools and secondary schools. The morbidities were 4.14, 2.13 and 0.69 per thousand, respectively. Seventy four cooks in 15 clusters of diarrhea were Norovirus positive. The rate was 8.67%. Among these pathogens, Norovirus had the largest proportion , but the trend was declining. At least three kinds of genetype of GⅡ Norovirus were detected every year. Conclusion Clusters of diarrhea mainly occurred in kindergartens, primary schools and secondary schools. Result from the increasing proportions of unknown-cause clusters of diarrhea, the testing methods and scopes of pathogens should be extended. Diverse genetypes of Norovirus coexist and alternate in Beijing. So appearance of new genetypes and recombination of existed ones of Norovirus should be closely concerned.
