Hypersensitivity myocarditis confirmed by cardiac magnetic resonance imaging and endomyocardial biopsy.
10.3904/kjim.2014.29.2.236
- Author:
Yumi PARK
1
;
Sung Gyun AHN
;
Anna KO
;
Sang Ho RA
;
Jaehwang CHA
;
Yong Gwan JEE
;
Ji Hyun LEE
Author Information
1. Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea. sgahn@yonsei.ac.kr
- Publication Type:Case Reports
- Keywords:
Myocarditis;
Drug hypersensitivity;
Magnetic resonance imaging;
Biopsy
- MeSH:
Aged;
Amoxicillin/*adverse effects;
Anti-Bacterial Agents/*adverse effects;
*Biopsy;
Drug Hypersensitivity/*diagnosis/drug therapy/etiology/pathology;
Electrocardiography;
Female;
Glucocorticoids/therapeutic use;
Humans;
*Magnetic Resonance Imaging;
Myocarditis/chemically induced/*diagnosis/drug therapy/pathology;
Myocardium/*pathology;
Predictive Value of Tests;
Prednisolone/therapeutic use;
Risk Factors;
Treatment Outcome
- From:The Korean Journal of Internal Medicine
2014;29(2):236-240
- CountryRepublic of Korea
- Language:English
-
Abstract:
Myocarditis often occurs due to viral infections and postviral immune-mediated responses. Hypersensitivity myocarditis is a rare form of myocarditis. Numerous drugs can induce myocarditis, which is typically reversible after withdrawal of the causative agent. Here, we report a case of hypersensitivity myocarditis that was probably triggered by amoxicillin and that resolved completely with heart failure management as well as discontinuation of the drug. A 68-year-old woman presented with acute chest pain mimicking acute coronary syndromes, but the coronary angiography was normal. A recent history of taking medications, skin rash, and peripheral eosinophilia suggested a diagnosis of hypersensitivity myocarditis, which was confirmed by cardiac magnetic resonance imaging and endomyocardial biopsy.
