Management of oral mucositis owing to chemical burn by intoxication of agricultural chemicals(gramoxon): report of cases.
- Author:
Jae Ha YOO
1
;
Sang Hoon KANG
;
Hyun Sil KIM
;
Sang Hum BAEK
;
Tae Min YOU
;
Ji Woong LEE
;
Won Gyun CHUNG
;
Jong Bae KIM
Author Information
1. Department of Oral and Maxillofacial Surgery, College of Dentistry, Yonsei University, Korea. nursekhm@freechal.com
- Publication Type:Case Report
- Keywords:
Agricultural intoxication;
Chemical burn;
Oral mucositis;
Paraquat intoxication
- MeSH:
Agrochemicals;
Bandages;
Blister;
Burns, Chemical*;
Corrosion;
Desiccation;
Diet;
Diuresis;
Fibrosis;
Gastric Lavage;
Glucose;
Hemoperfusion;
Hemorrhage;
Human Body;
Hyalin;
Korea;
Lidocaine;
Membranes;
Mouth Mucosa;
Mucositis;
Paraquat;
Prednisolone;
Pulmonary Edema;
Respiration;
Stomatitis*;
Superoxides
- From:Journal of the Korean Association of Oral and Maxillofacial Surgeons
2003;29(2):123-127
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Chemical burns onto oral mucosa which are infrequent, may result from contact with a wide variety of chemical agents. The degree of injury depends on the chemical, its concentration, duration of contact, and the natural penetrability and resistance of the tissues involved. Chemicals do not usually "burn" in that they do not cause destruction by hyperthermic activity. Rather, they damage tissue by causing coagulation of protein by one of several processes, reduction, oxidation, desiccation, corrosion, or vesication. Paraquat(Gramoxon) is the most frequently agricultural chemicals that induce the severe toxic reactions onto the organs of human body in Korea. The toxic reaction are composed of pulmonary edema and fibrosis, formation of hyaline membrane, inflammatory reaction and bleeding tendency, owing to the cell damage by the production of superoxide radicals. The contents of essential treatment in paraquat intoxication are commonly airway and breathing maintenance, gastric lavage, much hydration and diuresis, hemoperfusion and medications for the removal of the chemicals and the prevention of various complications. The sedative oral dressings, such as, orabase ointment application, warm saline gargling, lidocaine viscous gargling and oral gargling by the mixed solutions(tetracycline, prednisolone and 10% dextrose water) are important for the improvement of chemical oral mucositis and the comfortable feeding of diet. The authors managed properly two cases of oral chemical mucositis that were occurred by the incorrect use of agricultural chemicals(paraquat) and report the cases with the review of literatures about care of the chemical intoxication and oral mucositis.
