Acute Ischemic Stroke in a Patient with Metastatic Gastric Cancer after Ramucirumab Chemotherapy
- Author:
Sumin KIM
1
;
Sorae LEE
;
Jun-Sang SUNWOO
Author Information
- Publication Type:Case Report
- From:Journal of the Korean Neurological Association 2024;42(3):251-254
- CountryRepublic of Korea
- Language:Korean
- Abstract: Ramucirumab is a vascular endothelial growth factor (VEGF) receptor-2 inhibiting monoclonal antibody for the treatment of gastric cancer, non-small cell lung cancer, colorectal cancer, and hepatocellular carcinoma. Some VEGF inhibitors are known to increase the risk of ischemic stroke; however, their association with ramucirumab remains controversial. To the best of our knowledge, only two cases of ischemic stroke following ramucirumab treatment have been reported worldwide. We herein present the first case of acute cerebral infarction secondary to ramucirumab in Korea.
