Evidence-Based Review on Symptomatic Management of Huntington’s Disease
- Author:
Jung Hwan SHIN
1
;
Hui-Jun YANG
;
Jong Hyun AHN
;
Sungyang JO
;
Seok Jong CHUNG
;
Jee-Young LEE
;
Hyun Sook KIM
;
Manho KIM
;
Author Information
- Publication Type:2
- From:Journal of Movement Disorders 2024;17(4):369-386
- CountryRepublic of Korea
- Language:English
- Abstract: Huntington’s disease (HD) is a neurodegenerative disorder characterized by motor, behavioral, and cognitive impairments and significant impacts on patient quality of life. This evidence-based review, conducted by the Korean Huntington Disease Society task force, systematically examines current pharmacological and nonpharmacological interventions for symptomatic management of HD. Following PRISMA guidelines, databases were searched for studies up to August 2022 that focused on 23 symptoms across four domains: motor, neuropsychological, cognition, and others. This review provides a comprehensive and systematic approach to the management of HD, highlighting the need for more high-quality clinical trials to develop robust evidence-based guidelines.
