Efficacy and Safety of Zolpidem for Musician’s Dystonia
- Author:
Shiro HORISAWA
1
;
Kilsoo KIM
;
Masato MURAKAMI
;
Masahiko NISHITANI
;
Takakazu KAWAMATA
;
Takaomi TAIRA
Author Information
- Publication Type:12
- From:Journal of Movement Disorders 2024;17(4):425-429
- CountryRepublic of Korea
- Language:English
-
Abstract:
Objective: The efficacy and safety of zolpidem for treating musician’s dystonia are not well understood. We aimed to retrospectively investigate the efficacy and safety of zolpidem for treating musician’s dystonia.
Methods: We retrospectively reviewed medical records between January 2021 and December 2023 to identify patients with musician’s dystonia who had been prescribed zolpidem. Tubiana’s Musician’s Dystonia Rating Scale (range, 1–5; lower scores indicating greater severity) was used to evaluate musician’s dystonia.
Results: Fifteen patients were included in this study. The mean effective dose of zolpidem was 5.3 ± 2.0 mg. The mean effective duration of zolpidem was 4.3 ± 1.2 h. With zolpidem administration, Tubiana’s musician’s dystonia rating scale score significantly improved from 2.2 ± 1.0 to 4.3 ± 0.8 (48.9% improvement, p < 0.001). Two patients (13.3%) discontinued the drug owing to unsatisfactory results or sleepiness.
Conclusion: The results of this study suggest that zolpidem may be an alternative treatment option for musician’s dystonia.
