Bromate Intoxication Associated with Acute Renal Failure.
- Author:
Kyoung Il SONG
1
;
Su Hee KIM
;
Jin Geun JANG
;
Jong Soo CHOI
Author Information
1. Department of Internal Medicine, College Medicine, Ulsan University, Asan Kangnung Hospital, Kangnung Korea.
- Publication Type:Case Report
- Keywords:
Bromate intoxication;
Acute renal failure
- MeSH:
Acute Kidney Injury*;
Adult;
Anemia, Hemolytic;
Anuria;
Blindness;
Central Nervous System;
Chungcheongnam-do;
Deafness;
Depression;
Dialysis;
Diarrhea;
Early Intervention (Education);
Eating;
Female;
Hearing Loss;
Humans;
Renal Dialysis;
Renal Insufficiency;
Sodium;
Vomiting
- From:Korean Journal of Nephrology
2001;20(4):732-735
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Bromate salt is very toxic oxidant. The clinical manifestations of bromate intoxications are vomiting, diarrhea, depression of central nervous system, oliguric or non-oliguric renal failure, hemolytic anemia and deafness. Most of the toxic manifestations are reversible with the exception of renal failure and deafness. Since bromate is a small hydrophilic molecule, its removal by dialysis, especially hemodialysis, can reasonably be expected. Since the serious complications such as deafness, acute renal failure usually occur concurrently within 4-16 hours after ingestion, dialysis should therefore be considered in every patient presenting within a few hours of a significant amount of bromate. Recently, we encountered a 40-year-old female, past hairdresser, who was admitted to Asan Kangnung Hospital due to frequent diarrhea, vomiting and anuria after ingestion of sodium bromate. The patient required regular hemodialysis therapy and has not any evidence of complication such as hearing loss, blindness and irreversible renal failure. The clinician must assess the potential for preventing irreversible ototoxicity and nephrotoxicity and weigh the importance of early intervention against the possible risks of aggressive treatment in bromate intoxication.
