A case of primary antiphospholipid syndrome with renal microangiopathy.
- Author:
Choong Heon RHEE
1
;
Jae Hyun KOH
;
Hoon Suk CHA
;
Jinseok KIM
;
Wooseong HUH
;
Eun Mi KOH
;
Mi Kyung KIM
Author Information
1. Department of Medicine and Diagnostic Pathology, Sungkyunkwan University School of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Antiphospholipid syndrome;
Antiphospholipid antbody;
Renal microangiopathy
- MeSH:
Adult;
Antibodies;
Antiphospholipid Syndrome*;
Blood Proteins;
Glomerulonephritis, IGA;
Humans;
Korea;
Livedo Reticularis;
Lupus Erythematosus, Systemic;
Male;
Phospholipids;
Thrombocytopenia;
Thrombosis;
Thrombotic Microangiopathies
- From:Korean Journal of Medicine
2001;61(1):86-90
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Antiphospholipid syndrome is a disease that has continuous high titer of antibodies directed against either phospholipids or plasma proteins bound to anionic phospholipids in serum and shows a variety of clinical manifestations including recurrent venous and arterial thrombosis, recurrent fetal losses, livedo reticularis and thrombocytopenia. Because thrombosis may develop in any vessel, clinical manifestations are variable. Renal microangiopathy has been reported in antiphospholipid syndrome associated with systemic lupus erythematosus and rarely reported in primary antiophospholipid syndrome. But there was no case report of antiphospholipid syndrome accompanied by renal microangiopathy in Korea. Recently, we experienced a 25 years old male patient who had primary antiphospholipid syndrome with intrarenal thrombotic microangiopathy and IgA nephropathy. So, we report this case with review of relevant literature.
