The Effect of Posterior Subtenon Triamcinolone Injection in Panretinal Photocoagulation Induced Visual Dysfunction of Diabetic Retinopathy.
10.3341/jkos.2009.50.6.864
- Author:
Hyung Bin HWANG
1
;
Young Hoon PARK
Author Information
1. Department of Ophthalmology and Visual Science, College of Medicine, The Catholic University of Korea, Seoul, Korea. parkyh@catholic.ac.kr
- Publication Type:Original Article
- Keywords:
Panretinal photocoagulation;
Posterior sub-Tenon's capsule injection of Triamcinolone acetonide
- MeSH:
Diabetic Retinopathy;
Eye;
Follow-Up Studies;
Hand;
Humans;
Light Coagulation;
Macular Edema;
Ophthalmic Solutions;
Triamcinolone;
Triamcinolone Acetonide;
Visual Acuity
- From:Journal of the Korean Ophthalmological Society
2009;50(6):864-869
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To evaluate the efficacy of a prophylactic posterior sub-Tenon's capsule injection of Triamcinolone acetonide (TA) against macular edema and visual dysfunction by panretinal photocoagulation (PRP) in patients with severe nonproliferative and proliferative diabetic retinopathy. METHODS: Thirty-eight eyes of 19 patients who have diabetic retinopathy without macular edema and whose retinopathy was bilateral and symmetrical were evaluated. Triamcinolone was injected into the posterior sub-Tenon's capsule in one eye of the patients and nothing was injected in the other eye as a control. Two weeks later, PRP was performed every other week for 4 sessions on both eyes in all patients. The clinical course of visual acuity and macular edema was monitored for up to approximately 6 months after the initial PRP. RESULTS: There was no statistically significant difference of visual acuity before PRP in the 2 groups (p>0.05), and there was no macular edema in any patient. For a follow-up period of 6 months, visual dysfunction was more severe in the TA-injected eye than the control. However, the difference was not statistically significant (p>0.05) throughout the follow-up period except at the 20-week time point. On the other hand, macular edema occurred in 2 eyes (10.5%) of the TA-injected group, and in 4 eyes (21.1%) of the control group. IOP elevation as a complication caused by TA-injection occurred in 2 eyes (10.5%). However, IOP was controlled successfully by anti-glaucomatic eye drops. CONCLUSIONS: Posterior sub-Tenon's capsule injection of Triamcinolone is a safe and effective treatment modality for preventing PRP-induced visual dysfunction and macular edema.
