A Case Report of Postoperative Herpes Simplex Viral Pneumonia in a Patient with Tracheal Adenoid Cystic Carcinoma.
- Author:
Jae Chul HWANG
1
;
Young Hwa CHOI
;
Hye Jin CHO
;
Yoon Jung OH
;
Hyun Ee YIM
;
Kwang Joo PARK
;
Yi Hyeong LEE
Author Information
1. Department of Pulmonology and Critical Care Medicine, Ajou University School of Medicine, Suwon, Korea. yhwa1805@madang.ajou.ac.kr
- Publication Type:Case Report
- Keywords:
Herpes simplex virus;
Pneumonia;
Adenoid cystic carcinoma;
Steroid;
Bronchoalveolar lavage
- MeSH:
Acyclovir;
Adenoids*;
Adrenal Cortex Hormones;
Aged;
Bronchoalveolar Lavage;
Bronchoscopy;
Carcinoma, Adenoid Cystic*;
Constriction, Pathologic;
Cough;
Diagnosis;
Drug Therapy;
Dyspnea;
Eosinophils;
Epithelial Cells;
Female;
Herpes Simplex*;
Humans;
Immunocompromised Host;
Immunohistochemistry;
Infant, Newborn;
Intranuclear Inclusion Bodies;
Pneumonia;
Pneumonia, Viral*;
Respiratory Distress Syndrome, Adult;
Respiratory System;
Simplexvirus;
Trachea
- From:Korean Journal of Infectious Diseases
2002;34(1):64-68
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Herpes simplex virus (HSV) infection of the lower respiratory tract occurs rarely in neonate and immunocompromised host. The need for a timely and specific diagnosis of viral infections is becoming greater with development of antiviral chemotherapy. Herein, we report a case of herpes simplex virus pneumonia diagnosed by cytologic examination of the bronchoalveolar lavage (BAL) sample of respiratory epithelial cells in a tracheal adenoid cystic carcinoma patient. A 65-year-old woman presented with dyspnea and cough for one month. Bronchoscopy showed a mass arising from the posterior wall of upper trachea, and she underwent tracheal sleeve resection with cricotracheal anastomosis. The pathologic examination revealed adenoid cystic carcinoma. Corticosteroids were used for prevention of stenosis and swelling on the anastomosis site. On 28th postoperative day, pneumonia developed and it was aggravated despite of antibiotic therapy. The cytologic examination of the BAL fluid showed the eosinophilic nuclear inclusion along with the positive result of immunocytochemistry using monoclonal antibody to HSV. Despite of immediate therapy with acyclovir the pneumonia progressed to the acute respiratory distress syndrome and the patient eventual died.
