One case of Subacute Sensory Neuropathy Associated with Primary Sjogren's Syndrome.
- Author:
Won Heu CHUNG
1
;
Keun Ho JUNG
;
Dong Gyun HAN
;
Heue Jung PARK
;
Phil Za CHO
;
Seung Min KIM
;
Il Nam SUNWOO
Author Information
1. Department of Neurology, National Medical Center, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Peripheral neuropathy;
Sjogren's syndrome;
Sensory neuropathy;
Dorsal root ganglia
- MeSH:
Action Potentials;
Axons;
Biopsy;
Female;
Ganglia, Spinal;
Humans;
Inflammation;
Myelin Sheath;
Peripheral Nervous System Diseases;
Sjogren's Syndrome*;
Sural Nerve
- From:Journal of the Korean Neurological Association
1999;17(5):735-740
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Subacute sensory neuropathies associated with primary Sjogren's syndrome have been reported rarely. We describe a woman with primary Sjogren's syndrome who developed a widespread, pure sensory neuropathy with a subacute onset. An electrophysiological study showed the typical absence or decreased amplitude of sensory nerve action potentials (SNAPs). A sural nerve biopsy showed a loss of large myelinated fibers and axonal degeneration without inflammation. The clinical course of long-standing subacute sensory neuropathy, the biopsy-documented axonal degeneration, and the neurophysiological findings suggest involvement of the dorsal root ganglia.
