A Case of Marchiafava-Bignami Disease with Reversible Brain MRI Findings of Corpus Callosal Lesions.
- Author:
Jae hoon JOUNG
1
;
Ki Bum SUNG
;
Mu Young AHN
;
Hyun Kil SHIN
;
Hyung Kook PARK
Author Information
1. Department of Neurology, College of Medicine, Soonchunhyang University.
- Publication Type:Case Report
- Keywords:
Chronic alcoholism;
Marchiafava-Bignami disease;
MRI
- MeSH:
Alcoholics;
Alcoholism;
Brain*;
Corpus Callosum;
Dysarthria;
Humans;
Magnetic Resonance Imaging*;
Marchiafava-Bignami Disease*;
Middle Aged;
Neurologic Manifestations;
Seizures;
Vitamins
- From:Journal of the Korean Neurological Association
1999;17(5):761-763
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Marchiafava-Bignami disease(MBD), characterized by the primary degeneration of the corpus callosum, is a rare complication of chronic alcoholism. Recently, a few cases of MBD with reversible neuro-imaging abnormalities were reported. A 58-year-old, chronic alcoholic man was admitted with mental change, dysarthria, and a seizure attack. A T2-weighted Brain magnetic resonance imaging demonstrated high signal intensities in the body and splenium of the corpus callosum, multiple white matter, and cortical gray matter. Treatment with a multiple vitamin complex resulted in a near complete recovery of neurological manifestation. A brain MRI obtained four weeks after admission revealed a dramatic resolution of previous imaging abnormalities. We report a case of Marchiafava-Bignami disease with reversible neuro-imaging abnormalities.
