Two Cases of Marchiafava-Bignami Disease.
- Author:
Byeong Cheol OH
1
;
Yun Jeong YANG
;
Young Hyun KIM
Author Information
1. Department of Neurology, Chonbuk National University Medical School.
- Publication Type:Case Report
- Keywords:
Marchiafava-Bignami disease;
Corpus callosum;
Demyelination
- MeSH:
Alcohol Drinking;
Corpus Callosum;
Deglutition Disorders;
Demyelinating Diseases;
Humans;
Magnetic Resonance Imaging;
Marchiafava-Bignami Disease*;
Nervous System Diseases;
Nutritional Support;
Seizures
- From:Journal of the Korean Neurological Association
1999;17(5):764-766
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We described 2 patients with Marchiafava-Bignami disease, a neurological disorder associated with chronic alcohol consumption. Patient 1 expressed general weakness and confusion, while patient 2 expressed dysphagia and seizures. Lesions involving the corpus callosum were identified with T2 weighted MR imaging in which there was a hyperintensity in the splenium of patient 1 and in the entire corpus callosum of patient 2. While the conditions of both patients were improved by with nutritional support, they were left with cognitive impairment.