A Case of Linear Hyperpigmentation after Bleomycin Treatment.
- Author:
Mu Hyun SONG
1
;
Kyung Suk OH
;
Young Lip PARK
;
Hyun JUNG
;
Kyu Uang WHANG
Author Information
1. Department of Dermatology, College of Medicine, Soonchunhyang University Seoul, Korea. happyskin@yahoo.co.kr
- Publication Type:Case Report
- Keywords:
Bleomycin;
Linear hyperpigmentation
- MeSH:
Adult;
Arm;
Bleomycin*;
Carcinoma, Squamous Cell;
Drug Therapy;
Erythema;
Gangrene;
Humans;
Hyperpigmentation*;
Nasopharynx;
Sclerosis;
Skin;
Veins
- From:Korean Journal of Dermatology
2001;39(9):1014-1016
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Bleomycin, an antitumor antibiotic, has several dose-related skin toxicities, including hyperpigmentation, sclerosis, gangrenes, nail changes, and erythema in certain selected skin sites. A case of hyperpigmentation in a linear pattern due to in tavenous injection of bleomycin in a 37-year-old man with squamous cell carcinoma at nasopharynx is described. After 9 months since bleomycin chemotherapy started, dark brownish colored linear hyperpigmentation developed along veins of the skin of both arms.