Practical issues of oral immunotherapy for egg or milk allergy
- Author:
Sukyung KIM
1
;
Kangmo AHN
;
Jihyun KIM
Author Information
- Publication Type:Review Article
- From: Clinical and Experimental Pediatrics 2024;67(3):140-148
- CountryRepublic of Korea
- Language:English
- Abstract: Oral immunotherapy (OIT) has been recommended to reduce parental burden related to strict allergen avoidance and induce desensitization and immune tolerance for patients with long-lasting allergies to hen’s eggs (HE) or cow’s milk (CM). OIT should be monitored by pediatric allergists specializing in OIT and oral food challenge tests to manage allergic reactions. Although a previous history of anaphylaxis or multiple food allergies is not a contraindication to OIT, it is contraindicated if the patient has uncontrolled asthma, a malignancy, active systemic autoimmune disorders, or diseases requiring treatment with beta-blockers. A variety of OIT protocols have been de veloped to ensure better outcomes and safe up-dosing, including adjunctive therapies with biologics. This review provides insight into the practical issues of various immunotherapy options for children with HE or CM allergies.
