Detection of Recurrence by 18F-FDG PET in Patients with Endometrial Cancer Showing No Evidence of Disease.
10.3346/jkms.2010.25.7.1029
- Author:
Sang Young RYU
1
;
Kidong KIM
;
Younha KIM
;
Sang Il PARK
;
Beob Jong KIM
;
Moon Hong KIM
;
Seok Cheol CHOI
;
Eui Don LEE
;
Kyung Hee LEE
;
Byung Il KIM
Author Information
1. Department of Obstetrics & Gynecology, Korea Cancer Center Hospital, Korea Institute of Radiological and Medical Sciences (KIRAMS), Seoul, Korea. ryu@kcch.re.kr
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Endometrial Neoplasms;
Recurrence;
Positron-Emission Tomography
- MeSH:
Adult;
Aged;
Endometrial Neoplasms/*diagnosis/pathology/*radionuclide imaging;
Female;
Fluorodeoxyglucose F18/*diagnostic use;
Humans;
Middle Aged;
Neoplasm Recurrence, Local/*diagnosis/pathology/*radionuclide imaging;
Positron-Emission Tomography/*methods;
Predictive Value of Tests;
Retrospective Studies;
Sensitivity and Specificity
- From:Journal of Korean Medical Science
2010;25(7):1029-1033
- CountryRepublic of Korea
- Language:English
-
Abstract:
This study assessed the feasibility of F-18-fluorodeoxyglucose positron-emission tomography (18F-FDG PET) in the post-therapy surveillance for patients with endometrial cancer showing no evidence of disease (NED). From April 1997 to June 2007, 127 patients with endometrial cancer showing NED were performed 18F-FDG PET scan. The feasibility of 18F-FDG PET for the early detection of recurrence in patients with endometrial cancer was evaluated retrospectively. Of the 127 patients, 32 patients showed positive lesions on 18F-FDG PET scan. Nineteen (19/127 cases, 15%) of them were confirmed to have a recurrence clinically or histologically. The sensitivity, specificity and positive and negative predictive value of 18F-FDG PET for detecting recurrences in patients with endometrial cancer were 100%, 88%, 59% and 100%, respectively. In conclusion, 18F-FDG PET may be a useful method for the post-therapy surveillance in patients with endometrial cancer.
