Feasibility and Safety of Extensive Upper Abdominal Surgery in Elderly Patients with Advanced Epithelial Ovarian Cancer.
10.3346/jkms.2010.25.7.1034
- Author:
Myong Cheol LIM
1
;
Sokbom KANG
;
Yong Jung SONG
;
Sae Hyun PARK
;
Sang Yoon PARK
Author Information
1. Branch of Uterine Cancer, Research Institute and Hospital, National Cancer Center, Goyang, Korea. sokbom@ncc.re.kr
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Ovarian Neoplasms;
Surgery;
Aged;
Extensive Upper Abdominal Surgery;
Complications;
Risk Factors
- MeSH:
Abdomen/*surgery;
Adult;
Age Factors;
Aged;
Disease-Free Survival;
Female;
*Gynecologic Surgical Procedures/adverse effects;
Humans;
Kaplan-Meiers Estimate;
Middle Aged;
Ovarian Neoplasms/mortality/*pathology/*surgery;
Retrospective Studies;
Treatment Outcome
- From:Journal of Korean Medical Science
2010;25(7):1034-1040
- CountryRepublic of Korea
- Language:English
-
Abstract:
We performed a retrospective study to evaluate the feasibility and safety of extensive upper abdominal surgery (EUAS) in elderly (> or =65 yr) patients with advanced ovarian cancer. Records of patients with advanced epithelial ovarian cancer who received surgery at our institution between January 2001 and June 2005 were reviewed. A total of 137 patients including 32 (20.9%) elderly patients were identified. Co-morbidities were present in 37.5% of the elderly patients. Optimal cytoreduction was feasible in 87.5% of the elderly while 95.2% of young patients were optimally debulked (P=0.237). Among 77 patients who received one or more EUAS procedures, 16 (20.8%) were elderly. Within the cohort, the complication profile was not significantly different between the young and the elderly, except for pleural effusion and pneumothorax (P=0.028). Elderly patients who received 2 or more EUAS procedures, when compared to those 1 or less EUAS procedure, had significantly longer operation times (P=0.009), greater blood loss (P=0.002) and more intraoperative transfusions (P=0.030). EUAS procedures are feasible in elderly patients with good general condition. However, cautious peri-operative care should be given to this group because of their vulnerability to pulmonary complications and multiple EUAS procedures.
